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Evidence level: Unsupported by the cited record Sources: Selective and membrane-permeable small molecule inhibitors of nicotinamide N-methyltransferase reverse high fat diet-induced obesity in mice., Nicotinamide N-methyltransferase inhibition mitigates obesity-related metabolic dysfunction., ClinicalTrials.gov exact-name search, accessed 2026-07-12 How to read this: Direct efficacy findings come from obese mice, not human trials

This lack of specificity poses a major obstacle to clinical translation, as s widespread distribution can damage healthy tissues dependent on normal iron metabolism and redox homeostasis

Leszczyniecka M, Roberts T, Dent P, Grant S, Fisher PB

ArticlePubMed 145

Front Immunol (2018) 9:2924

Sportler verwenden es vor allem, um ihren Krper zu einer effizienteren Umwandlung von Fett in Energie anzuregen