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USA 117 , 2763727645 (2020)

Firmness and fine line changes may take 4 to 8 weeks

In models of HFD feeding, diabetes, and insulin resistance, AX supplementation attenuates neuroinflammation, oxidative stress, and cognitive impairment, while modulating nutrient-sensing, inflammatory, and neuronal survival pathways [88,89,90,91]

Biochemical and biophysical research communications , 280 (1), 132138

Trial subjects reported improved skin hydration within 1-2 weeks, noticeable texture and firmness improvements at 4-8 weeks, and reduced fine lines with better skin resilience at 8-12+ weeks