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P.et al (2020c)

Pt 1Biochem

Dry : Pat your skin dry with a clean towel

The presentation of immobilized antigen-antibody complexes on cartilage provides an exceptionally good substrate for complement fixation, similar to rheumatoid factor embedded in rheumatoid cartilage

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Additionally, iron overload generates hydroxyl radicals via the Fenton reaction, causing mitochondrial membrane potential collapse in CD8+ T cells and inhibiting TCR signal transduction (as evidenced by downregulation of p-ZAP70), forming a vicious cycle of NETs-iron overload-immune suppression (155)