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Differentially expressed genes regulating glutathione metabolism, protein-folding, and unfolded protein response in pancreatic beta-cells in type 2 diabetes mellitus

The liver is also the major GSH supply organ

According to Gamelin et al

Metabolic intermediates for biosynthesis Despite the original idea of Warburg [2] that aerobic glycolysis was originated as a consequence of mitochondrial dysfunction, subsequent studies showed that mitochondria of cancer cells are still functional and able to conduct oxidative phosphorylation

Aquaculture 464:309315 Aboutabl ME, Zordoky BN, Hammock BD et al (2011) Inhibition of soluble epoxide hydrolase confers cardioprotection and prevents cardiac cytochrome P450 induction by benzo (a) pyrene