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Highlights The knockdown of KDM2B in basal-like breast cancer cell lines lowers the levels of GSH and sensitizes the cells to ROS inducers, GSH targeting molecules, and DUB inhibitors

Appl Microbiol Biotechnol 91 , 10011006 (2011)

These metabolic axes take part in shaping the ferroptosis-susceptible cell-state collectively, and the relative contribution of each axis is likely dictated by the cellular contexts and by the specific ferroptosis-inducing approaches (Fig

( 2 O 2 alone existed, it could induce increased GSH synthesis, enhanced GPx activity and upregulation of GCLC/GCLM expression

Pharmacological profile of Caesalpinia bonducella Flem