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D., and Townsend, C

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This decrease in the rearing behavior was dose and time-dependant and started 3 days after treatment with cannabis extract and continued throughout the study

J Immunol (2009) 182(9):58009.10.4049/jimmunol.0801873 31 ZhangXWheelerDTangYGuoLShapiroRARibarTJet alCalcium/calmodulin-dependent protein kinase (CaMK) IV mediates nucleocytoplasmic shuttling and release of HMGB1 during lipopolysaccharide stimulation of macrophages

It was demonstrated in animal model using the GSTP -/- knockout mice and their wild type counterpartsthe GSTP -/- knockout mice showed a faster development of TPA (13-acetate-12-O-tetradecanoylphorbol) induced by human papilloma compared to their wild type [17]