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Indones Biomed J

neurodegenerative diseases

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In this regard, it has been proposed that a viral infection in which selfantigens that generate molecular mimicry with myelin proteins cause a loss of tolerance against it, which results in the destruction of myelin mediated by activated T lymphocytes in white matter of the brain and sometimes extending into the gray matter, resulting in defects in the conduction of nerve impulses that leads to symptoms, depending on the affected site of the brain or spinal cord [1] (Figure 1)

Karimi, M., Pirzad, S., Hooshmand, F., Shirsalimi, N., & Pourfaraji, S