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Further, oxidative stress has been proven to facilitate the accumulation of strands of amyloid-beta proteins, normally present in the brain, to form amyloid plaques, which have classically been considered to be the cause and thus, the treatment target of Alzheimers disease

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Since cisplatin-induced hearing loss was first reported 9 , numerous studies have investigated the physiological features and mechanisms of ototoxicity caused by cisplatin

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Anaesthesist 45(4):343350 Spies CD, Reinhart K, Witt I, Meier-Hellmann A, Hannemann L, Bredle DL, Schaffartzik W (1994) Influence of N-acetylcysteine on indirect indicators of tissue oxygenation in septic shock patients: results from a prospective, randomized, double-blind study

Thus, while identifying ferroptosis as an aspect of the macrophage in CD, much remains to be done to understand the physiological and pathophysiological implications of death pathways in myeloid cells