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Kupffer cell-derived Tnf triggers cholangiocellular tumorigenesis through JNK due to chronic mitochondrial dysfunction and ROS

However, issues with short half-life in plasma (510 min), poor solubility, and toxicity have led to other alternatives with enhanced lipophilicity

10.1016/j.jnutbio.2015.08.001 66 HussainT.TanB.YinY.BlachierF.TossouM

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