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Larger, multi-center trials with standardized protocols are essential to confirm SFNs benefits and understand optimal dosing, treatment duration, and long-term safety

Quantification reactions were performed in triplicate for each sample using the Ct method with hypoxanthine-guanine phosphoribosyltransferase ( hprt ) serving as the reference housekeeping gene

Ballmer-Weber BK, Fernandez-Rivas M, Beyer K, Defernez M, Sperrin M, Mackie AR et al (2015) How much is too much

IU, international units

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