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CrossRef Cardiovascular Risk Is Elevated in Lean Subjects with Nonalcoholic Fatty Liver Disease Yuna Kim, Eugene Han, Jae Seung Lee, Hye Won Lee, Beom Kyung Kim, Mi Kyung Kim, Hye Soon Kim, Jun Yong Park, Do Young Kim, Sang Hoon Ahn, Byung-Wan Lee, Eun Seok Kang, Bong-Soo Cha, Yong-ho Lee, Seung Up Kim Gut and Liver .2022

Histochemical study of aldehyde dehydrogenase in the rat CNS

The exact time depends on the patient and the condition

MLC4: 8.066, 10.312, 10.983, 11.797, 16.096

Lipid peroxidation and MitoSOX measurements Cells were seeded in 6-well plates or 12-well plates at 0.1 to 0.3 million or 0.05 to 0.2 million cells per well overnight before treatment, respectively

Results Blocking the mevalonate pathway induces an ATF4-dependent adaptive response We previously reported that transcriptomic profiling of neuroblastoma SMS-KCNR cells treated with vehicle (DMSO) or simvastatin (5 M) identified 275 genes upregulated by simvastatin (Table S1) 13