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Ni, S., Yuan, Y., Kuang, Y

In fact, Al binds to the negatively-charged carboxyl groups of pectins, and both Al-induced ROS and free Al 3+ can disrupt the cell wall, producing modifications that could in turn reduce elasticity, due to the cleavage of polysaccharides or methyl esterification (Yang et al., 2010

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The researchers documented profound signs of mitochondrial damage, cellular energy exhaustion, and massive lipid oxidative damage in the patient cohorts

It is also associated with inflammation and oxidative stress, along with other pathological processes (195)

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