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The effect is likely explained by an increased unmeasured comorbidity burden in the high BBB-permeability group, which should in principle also raise the Alzheimer's risk, 73 thereby reducing our effect size

Kwon, D.R., & Park, G.Y

Western blotting also showed that suppressing c-Met expression downregulates the expression of NGF, N-cadherin, and Vimentin but upregulated the expression of E-cadherin (Fig

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Although brain infarction volume reduction did not reach statistical significance, motor performance in the rotarod test significantly recovered in DSIP-treated animals compared to vehicle controls confirming a functionally relevant neuroprotective effect at the behavioural level and establishing intranasal delivery as a viable route for CNS DSIP research

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