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While several recent reviews have underscored the role of vitamin C as an anticancer agent (Yue and Rao, 2020), and in the reprogramming of stem cells (Lee Chong et al., 2019), herein we highlight these activities within a context of DNA damage, repair, and genomic stability

doi: 10.1111/j.1447-0756.2006.00410.x

Elevated levels of BCAAs (leucine, isoleucine, and valine) have been consistently observed in patients with type 2 DM (T2DM), potentially linking to both immune dysregulation and insulin resistance (Wang et al., 2011)

These studies suggest that mTOR plays a more complicated role than originally proposed and may function in a context-dependent manner to drive T cell subset differentiation under various pathological or physiological conditions

There is mounting evidence that prenatal exposure to pro-inflammatory cytokines induces impaired spatial memory, neuronal loss, and gliosis in the hippocampus.19 Moreover, neurodevelopmental injuries due to excessive pro-inflammatory cytokines increase susceptibility to schizophrenia.202122 Neurogenesis is defined as a coordinating process of generating new neurons from neural stem cells.23 Since the first report from animal studies24 and human postmortem studies of the hippocampal region,25 numerous studies have focused on adult neurogenesis