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In primary liver cell models, NAs are activated intracellularly by CYPs after cell entrance

[DOI] [PMC free article] [PubMed] [Google Scholar] 73.Zoulim F, Fournier C, Habersetzer F, Sprinzl M, Pol S, Coffin CS, Leroy V, Ma M, Wedemeyer H, Lohse AW, Thimme R, Lugardon K, Martin P, Bastien B, Sansas B, Adda N, Halluard C, Bendjama K, Brandely M, Inchausp G

Brain magnetic resonance imaging and upper gastrointestinal endoscopy may also be indicated in certain circumstances

Separation was carried out using a non-isocratic method (40%-50% methanol over 10 min) at ambient temperature and a flow rate of 0.3 mL/min

Injection site reactions: Mild redness or irritation possible, as with any injection

Pathogenic effects of novel mutations in the P-type ATPase ATP13A2 (PARK9) causing Kufor-Rakeb syndrome, a form of early-onset parkinsonism