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The brain doesn't stop making neurotransmitters entirely, but the output is reduced, and the balance shifts in ways that can show up as anxiety, low mood, or both simultaneously

This widespread insufficiency provides a logical rationale for choline supplementation: correcting a common dietary gap may help restore normal fat-processing function in the liver

Despite decades of research, no cure exists, and current treatments focus primarily on symptom management rather than altering the disease trajectory (Sun and Zhang, 2024)

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