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Testosterone inhibits immunoglobulin production by human peripheral blood mononuclear cells

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Under all treatments, CYS4 , HOM2 , HOM6 , MET6 , MET17 , SAH1 , SAM2 , and SHM2 were consistently up-regulated, only CYS3 was up-regulated in UCD522, and only SAM1 was up-regulated in UCD932

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167,168,169 These findings have driven the development of other HDAC inhibitors, with the expectation of elevated safety and efficacy in vivo

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