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Cell (2011) 144(5):64674

Gonalves, S

Growth hormone replacement therapy in the elderly with hypothalamic-pituitary disease: a dose-finding study

Glutamate can be further converted to -ketoglutarate (-KG) through oxidative deamination by glutamate dehydrogenase (GLUD1) or transamination by glutamate-linked transaminase as an anaplerotic substrate in the TCA cycle for energy production (Figure 1)