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The American Heart Association includes CRAO in its definition of an acute ischemic stroke, a sudden episode of neurological dysfunction caused by a lack of blood flow to the brain, spinal cord, or retina

One report suggested that frataxin promotes the interaction between NFS1 and substrate (Pandey et al., 2013), while frataxin was reported to promote sulfide transfer from NFS1 to ISCU1 (Parent et al., 2015)

doi: 10.1093/hmg/ddac291 81 KiaeeFZaki-DizajiMHafeziNAlmasi-HashianiAHamedifarHSabzevariAet al

Blanco-Mello et al

[1] Isopeptide bonds lead to branching in the primary sequence of a protein