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Classification and monitoring of adult leukemia by flow cytometry

Overall, there are only very subtle differences at the residue level between the inward-facing substrate free and the ipratropium-bound structures

doi: 10.1016/j.molimm.2007.03.024 91 ClassenCFBirdPIDebatinKM

NPJ Park Dis (2021) 7:27

the first and the second, participate actively in the regulation of cholinergic and dopaminergic synapses (Figure 1b), such as acute phase signaling, with AMBP (FM/C ratio: 1.10), APOH (FM/C ratio: 1.32), CO4B (FM/C ratio: 0.86), and KLKB1 (FM/C ratio: 0.88) as altered proteins

Instead of macrophages being either M1- or M2-polarized, they are mostly somewhere in between, often expressing both types of markers simultaneously ( TAMs are mainly M2-like anti-inflammatory macrophages with the ability to reduce a potent anti-tumor immune response