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For instance, if a patient switched from atorvastatin to rosuvastatin, both were explicitly recorded rather than collapsed under statin therapy. This ensured a precise representation of pharmacological history, enhancing the models ability to capture drug-disease interactions

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Further information and requests for resources and reagents should be directed to and will be fulfilled by the lead contact, Lei Li ([email protected])

By preventing its activation, KPV significantly downregulates the downstream transcription of pro-inflammatory cytokines, including: Tumor Necrosis Factor-Alpha ( TNF-$\alpha$ ) Interleukin-1 Beta ( IL-1$\beta$ ) Interleukin-6 ( IL-6 ) PepT1 Transporter Affinity Unlike larger, fragile peptide sequences, KPV leverages the PepT1 (Peptide Transporter 1) mechanism