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Nickel chloride (NiCl 2 )-caused inflammatory responses via activation of NF-B pathway and reduction of anti-inflammatory mediator expression in the kidney

J Agric Food Chem 62:860866

Am J Physiol Gastrointest Liver Physiol

Inflammatory mediators, including cytokines, chemokines, and reactive oxygen species (ROS), are released during I/R and travel to the brain, where they can directly damage the BBB and promote neuroinflammation (Song et al., 2020)