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Holly Ferkett 1993 Red Maple, Tulip Tree 5

Recent studies have shown that SIRT1 exerts a neuroprotective effect in MPP+-treated dopaminergic neurons, primarily through deacetylation of PKM2, which improves brain lactate homeostasis and upregulates PGC-1 expression, promoting mitochondrial biogenesis in MPP+-treated cells 8,41

Xia L, Tan S, Zhou Y, Lin J, Wang H, Oyang L, et al

Non-adipocyte fatty acids are mediated primarily through the transmembrane protein CD36, fatty acid transport proteins (FATPs), and fatty acid-binding proteins (FABPs)

(2018, September 13)

While these provide ALA rather than direct EPA and DHA, they contribute to overall anti-inflammatory status and support hormone balance