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Smokers melanosis . Oral pigmentation seen in heavy smokers . Investigations have shown ability of melanin to bind to noxious substances. . Exposure to polycyclic amines ( Nicotine & benzpyrene) has shown Smoker's melanosis Wikipedia Riehl Melanosis MD Searchlight Pigmented lesions of the oral cavity: An Update PMC What Caused These Multiple Hyperpigmented Macules of the Mouth? Plantar Hyperpigmentation MDedge
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