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albicans can finely regulate multiple iron uptake pathways such as high-affinity iron reduction systems and heme uptake through mechanisms such as the Sef1-Sfu1-Hap43 regulatory circuit and the iron-sulfur cluster assembly system, thereby promoting invasive and morphological transformation processes related to virulence, and accelerating the progression of infection (Zheng et al., 2025)

These findings were reinforced by a systematic review and meta-analysis by Henderson et al., which consolidated data from multiple neonatal studies and concluded that melatonin supplementation was associated with reduced oxidative damage and improved clinical outcomes (Henderson et al., 2018)

These developing approaches aim to deliver safer, more targeted options for managing cytokine dysregulation, offering promise across a range of inflammatory and autoimmune conditions

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Learning the common causes, what can trigger it, simple ways to find relief and when to see an eye doctor can help you better manage it

Finally, we critically evaluate the efficacy of current pharmacological and non-pharmacological approaches for the prevention and treatment of pediatric CIPN and discuss future advances in development of CIPN treatments