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Single colony isolates were used to validate the scanning allelic diversity pipelines

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Rather than viewing copper simply as a free metal ion, coordination chemistry explains how binding to a peptide creates a new chemical complex with distinct structural and physicochemical properties

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CLIC1 is an intracellular channel whose overexpression in cancer correlates with increased matrix stiffness (through the Wnt/-catenin/TCF4 signaling pathway) and altered glycolytic metabolism (Warburg effect), favoring tumor proliferation