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Regulation of hepatic lipogenesis by plasma free fatty acids: simultaneous studies on lipoprotein secretion, cholesterol synthesis, ketogenesis and gluconeogenesis

2022 NEJM) randomized 2,539 adults with overweight or obesity (without diabetes) to tirzepatide 5 mg, 10 mg, 15 mg, or placebo for 72 weeks

Its use is not associated with hGH side effects like insulin resistance, and it appears to be a safer alternative for researchers who want to investigate the fat-reducing properties of hGH without using intact hGH and exposing test subjects to its risks

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"FDA authorizes Pfizer COVID-19 vaccine for adolescents 12 to 15 years old"

Blood levels peak around 1-2 days post-injection and decline slowly