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26 Therefore, we suggest that hypertensive individuals with the 718C variant of the GPX4 gene are susceptible to CS because of the increased concentration or activity of the enzyme promoting proinflammatory processes and increasing the brain injury

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Targeting liposomes with transferrin elevated the BBB penetration of dopamine across a human BBB culture model [69]

Additionally, within the testosterone-stimulated granulosa cells, we validated the expression of key genes, confirmed senescence and sphingolipids dysregulation, and evaluated the therapeutic efficacy of the candidate agent

However, this observation is somewhat difficult to reconcile with modelled data (Polle 2001)