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Unlike oral supplements, an injection delivers vitamin B12 directly into the body without relying on digestive absorption which can be reduced by age, certain medications such as proton pump inhibitors or metformin, or gastrointestinal conditions

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This muscle autocrine/paracrine/endocrine effect has various effects

Allergic and clinical risks are the reason every B12 injection at CoLaz is given by a clinician trained in injection technique and emergency response, working under written protocols

There is no evidence that doses above 500mcg produce proportionally better results, and clinical trials using 1mg daily did not dramatically outperform lower doses

Personal or first-degree relative(s) history of multiple endocrine neoplasia type 2 or medullary thyroid carcinoma