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Y.FuK.et al (2019)

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Laparoscopic surgery is For safety reasons, your surgeon may switch from laparoscopic to open surgery after beginning the procedure

This degradation, in turn, allows NF-B activity to increase, resulting in increased transcription of pro-inflammatory genes, including TNF-, IL-1, IL-6, and inducible nitric oxide synthase (iNOS) (Morgan and Liu, 2011)