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10.1016/S0014-5793(01)03091-5 81 Gonzalez-GonzalezF

Secondly, since cardiomyocytes are easily affected by free iron overload, the release of excess free iron during ferroptosis would result in up-regulation of transferrin receptor (TFR) and down-regulation of ferritin, promoting cardiomyocyte cell death through mitochondrial VDAC2/3 or membrane lipid peroxidation through Fenton reaction to induce myocardial edema and dysfunction (Liu et al., 2018)

elegans cannot de novo synthesize sterols as they lack genes for squalene synthase and cyclase (34), and they require dietary cholesterol for development (35)

Digoxin, an overlooked agonist of ROR/RORT

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