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Artesunate and dihydroartemisinin may ameliorate lung tissue inflammation through the HMGB1/TLR4/NF-B pathway and alleviate lung injury induced by various factors, these compounds decrease inflammatory cell infiltration, immune cell (macrophages, neutrophils, eosinophils, and lymphocytes) counts, and inflammatory mediator (TNF-, IL-1, IL-6, IL-10, IL-12, and TGF-) levels (Li et al., 2023

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