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Yu M, Li H, Liu Q et al (2011) Nuclear factor p65 interacts with Keap1 to repress the Nrf2-ARE pathway

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Beyond immune exclusion, immune function is actively suppressed by tumors: elevated N- acetylaspartate (NAA) production disrupts the immunological synapse in CD8 + T and NK cells (178), while FGF21 derived from cancer cells rewires cholesterol metabolism toward inducing T-cell exhaustion (155)

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doi: 10.1038/srep30252 245 GuJChengYWuHKongLWangSXuZet al