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Description

Additionally, targeted therapies such as BRAF inhibitors (e.g., Vemurafenib) for patients with B-RAF mutations and CTLA-4 antibody ipilimumab provide new therapeutic possibilities alongside conventional chemotherapy (241)

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Studies showed that p.N410I, p.L413V, and p.N410T, three gene mutations in exon 10, can increase the activity of GDH (about twice the normal value) [13, 14]

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Nothing on this page is a recommendation to use these compounds in humans outside a licensed clinical or research context

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T.GreenwoodM

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2013;8:e80064

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Some anecdotal and small observational reports support vasodilator therapies for Raynauds

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