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In contrast, in models with GLS mutations, glutamate metabolism in tumor cells is restricted, which increases Gln concentration in the microenvironment and T-cell uptake and antitumor activity

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doi: 10.1038/s41591-018-0128-1 202 RobertsonM

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This is usually in the form of a cannula-over-needle device, in which a flexible plastic cannula comes mounted over a metal trocar

Prioritize hydration and fiber to aid clearance of conjugated byproducts