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and (iii) use of conditional knockout models (eg, neuron-specific GPX4 deficiency) to test whether acupunctures benefits are lost when ferroptosis defense is impaired

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However, with few exceptions showing significant results (Wang et al., 2016) against major pathogens for crop production like Botrytis cinerea , most silencing studies through RNA application were validated using transgenic materials that were over-expressing the transgenes (Dalakouras et al., 2016

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10.3390/plants12061289 [DOI] [PMC free article] [PubMed] [Google Scholar] El Hachlafi N., Fikri-Benbrahim K., Al-Mijalli S

Other studies have shown that GPX4 inactivation may increase susceptibility to ferroptosis in renal clear cell carcinoma by increasing lipid peroxidation (Zou et al., 2019)