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availability on the NHS is subject to local commissioning decisions and specific eligibility criteria, and it is not broadly recommended by NICE for routine adult weight management Orlistat a lipase inhibitor available on prescription or over the counter (as Alli) for weight loss support, in line with NICE guidance Structured NHS weight management programmes, including referral to specialist tier 3 or tier 4 services where clinically appropriate For concerns about growth hormone deficiency , a GP can refer patients to an endocrinologist for formal assessment

RNA isolation and quantitative reverse-transcription PCR (qRT-PCR) Total RNA was extracted from liver tissue or primary hepatocytes using the RNeasy Plus Mini kit (Qiagen, 74134)

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Treatment of adults with growth hormone (GH) deficiency with recombinant human GH

Christopher Raeburn, MD, Denver VA Hospital, Denver, CO