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The key mismatch driver is the constitutive hyperactivation of the nuclear factor erythroid 2-related factor 2 (Nrf2) antioxidant pathway in tumor cells

N Engl J Med 324(20):1385-93, 1991

(2020) developed a scaffold-free endometrial organoid model consisting of epithelial and stromal components that closely mimics the physiology of native endometrium