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The strengths of this study include multi-center design and homogenous (post-cardiovascular surgery) patient population

Paricalcitol treatment concentration (200 nM) was determined based on a previous study by 2 and 1% O 2 and balanced with 94% N 2 for 6 h, followed by 24 h of reoxygenation, while the H/R + paricalcitol group was reoxygenated in complete medium containing paricalcitol (200 nM) for 24 h

The findings indicated that 3 weeks of LC supplementation, in the amount 2-3 g/day, effectively alleviated pain [50,51,52,53]

Abdominal cramping: Usually temporary and may be mitigated by taking the supplement with a light meal

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