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For instance, when rats were orally administered 5 mg/kg of amygdalin, the following parameters were observed: T max was 14 min, C max was 23.08 ng/mL, area under the plasma concentration curve (0-t) (AUC 0t ) was 1,391.77 ng min/mL, area under the plasma concentration curve (0-) (AUC 0- ) was 1,569.22 ng min/mL, t 1/2 was 28.76 min, and MRT was 53.33 min (Zhang et al., 2022b)

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Rodrigo JP, Hernandez-Prera JC, Randolph GW, Zafereo ME , Hartl DM, Silver CE, Surez C, Owen RP, Bradford CR, Mkitie AA, Shaha AR, Bishop JA, Rinaldo A, Ferlito A

It was also evident that the dependent sample analysis by OPLS-EP analysis performed better compared to the independent sample analysis by OPLS-DA, both in terms of model quality parameter (Fig