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Antioxidant Protection Against Premature Aging Daily exposure to pollution and UV radiation accelerates skin aging

The overall pathophysiological relevance of the JNK amplification loop in the murine models of APAP- induced liver injury has been extensively shown with various JNK inhibitors and JNK gene silencing [42,64,65] as well as the protection by inhibition of upstream signaling events [56,57,59]