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Lack of improvement after six months may indicate need for protocol adjustment or additional interventions

Shoulder arthritis involving cartilage degeneration and bone changes typically does not improve significantly

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Starting it too late, or after bleeding has begun, significantly reduces its effectiveness

Discontinuing the protocol because of manageable discomfort means losing the cumulative biological benefits that GHK-Cu builds over weeks and months of consistent use

Acupuncture with non-noxious stimulation (0.8-T A , about 1.42mA) did not produce any significant influence on gastrointestinal motility