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B., Yang, Y., Xu, X

[DOI] [PMC free article] [PubMed] [Google Scholar] 12.Huang, Y., Todd, N

Antibiotics profoundly disrupt gut microbiota, transiently reducing IS/pCS production for weeks post-treatment, and phosphate binders such as sevelamer bind IS in the gut, lowering circulating levels independent of microbial production changes

OA is becoming more prevalent and burdensome, especially in the elderly population [2]

Taking it away from a heavy meal prevents it from being caught up in the complex digestive process of fats and fibers, which could potentially degrade the supplement before it reaches the bloodstream

Here is a more specific review of those issues