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IGF-1R-Independent ERK Pathway Activation MGF E-peptide activates ERK signalling in satellite cells and myoblasts via a receptor distinct from the IGF-1R

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Rituximab The anti-CD20 monoclonal antibody rituximab is approved for the treatment of many diseases, including non-Hodgkin lymphoma (NHL), chronic lymphocytic leukaemia (CLL) and rheumatoid arthritis [31]

Although direct interaction between 4-HNE and caspase-3 in psoriatic tissue is not fully confirmed, elevated caspase-3 activity and increased 4-HNE-protein adduct formation support its pro-apoptotic role [47,48]