Keywords: Flavins, Retbindin, Ariboflavinosis, Metabolism, Retinal degeneration, RPE dystrophy, Riboflavin Graphical abstract Abbreviations -SMA alpha smooth muscle actin CALCRL calcitonin receptor-like receptor COL2A collagen type II alpha 1 chain DEG differentially expressed genes DUSP1 dual specificity phosphatase 1 ECM2 extracellular matrix protein 2 EMT epithelial mesenchymal transition EGR1 early growth response 1 ERG electroretinography or electroretinograms FAD flavin adenine dinucleotide FMN flavin mononucleotide FOS fos proto-oncogene FPKM fragments per kilobase of transcript per million mapped reads Iba-1 Ionized calcium-binding adaptor molecule 1 IPL inner plexiform layer IS inner segments LAMA2 laminin subunit alpha MEPA1 prostate transmembrane protein, androgen induced 1 MEX-3C RNA-binding E3 ubiquitin ligase MRPL49 mitochondrial ribosomal protein L49 NR neural retina NR4A1 nuclear receptor subfamily 4 group OS outer segments OXL2 lysyl oxidase like 2 P postnatal day PDGFR platelet-derived growth factor receptor PNA peanut agglutinin PPM part per million Prph2 peripherin 2, aka Rds PRRX1 paired related homeobox 1 RC regular chow RDC riboflavin deficient chow RF riboflavin, aka, vitamin B2 RPE retinal pigment epithelium RPE65 retinal pigment epithelium protein 65, aka retinoid isomerohydrolase RPE-Ch retinal pigment epithelium-choroid Rtbdn retbindin TCA tricaboxylic cycle, aka Kreb's cycle or citric acid cycle VIM vimentin 1
Review: Advanced Atomic Force Microscopy Modes for Biomedical Research
Thus, prolonged periods of sub-optimal vitamin C exposure could have adverse health effects, including an increased susceptibility to a plethora of diseases
Metformin, cognitive function, and changes in the gut microbiome [J]
Skronska-Wasek, W
Yu, C., Gershwin, M
