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Compromised anti-ferroptosis defense in SOD1 G93A mice and ALS patient samples Because of Gpx4s unique role in reducing lipid hydroperoxides to suppress lipid peroxidation and regulate ferroptosis, we were also interested in determining the status of Gpx4 in SOD1 G93A mice

miR-382-5p, miRNA-382-5p

External compression of the superior vena cava: Superior vena cava syndrome typically causes upper body venous congestion, such as facial swelling, distended neck veins, and cyanosis, without significant lower extremity edema or signs of pulmonary hypertension

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Thus, we investigated here whether inactivation of inflammasome components can inhibit not only VEGFAinduced CNV, but also degenerative changes of the RPE and photoreceptors in aged VEGFA hyper mice

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