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Expert opinion Hunt et al 23 Data from randomized controlled trials and observational studies for parenteral treatment are lacking

Further analysis suggested that the peptide may have increased the ratio of Bcl-2/Bax, and potentially decreased cleaved caspase-3 and PARP levels, two markers of cell death

In stark contrast, Adipotide utilizes a mechanism of vascular targeting to induce apoptosis (programmed cell death) in the blood vessels supplying fat cells, causing the tissue to degrade via hypoxia

PMID: 60 GodingJWHowardMC

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