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doi: 10.1038/ng.2901, PMID: [DOI] [PMC free article] [PubMed] [Google Scholar] 47.Mancina RM, Dongiovanni P, Petta S, Pingitore P, Meroni M, Rametta R, et al

Food Funct 8(5):18101821

To evaluate the ability of molecules to interfere with aggregation of hCC while informing about cellular toxicity, cells were generated that produce and secrete WT and L68Q-hCC producing high-molecular weight complexes formed from the mutant protein

Importantly, unlike the strictly regulated ALOX enzymes, POR is ubiquitously expressed, suggesting that POR might be a constitutive fashion for lipid peroxidation