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Imaging studies have demonstrated that chronic cocaine users often exhibit brain atrophy and reduced gray and white matter volumes, particularly in the limbic regions essential for emotional processing and reward (Rando et al., 2013)

PMID 17517683

It has retained rights to the drug in mainland China, Hong Kong, Macau, and Taiwan.

Real-world data published in JAMA confirmed that tirzepatide was associated with significantly greater weight loss than semaglutide in clinical practice, not just in controlled trial settings