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Read and Holmes, 2017

Insights into the structureactivity relationship of a type III secretion system inhibitor, aurodox

An imbalance in the levels ROS and RNS can induce DNA damage, pathological sarcoplasmic reticulum (SR)/Ca 2+ leakage, mitochondrial impairment, and disruption of autophagic flux, causing lipid peroxidation-associated ferroptosis and diverse types of regulated cell death (e.g., apoptosis, pyroptosis) [27]